Paul D. Stein, MD, and Fadi Matta, MD's Acute Pulmonary Embolism - Current Problems in PDF

By Paul D. Stein, MD, and Fadi Matta, MD

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Extra resources for Acute Pulmonary Embolism - Current Problems in Cardiology-Vol.35, July 2010 No. 7, p307

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165) Heparin in the Treatment of Acute Pulmonary Embolism The rationale for initial treatment with UFH or LMWH is to rapidly prevent the formation of new thrombi in the lower extremities while giving thrombi already present time to adhere to the venous walls, and to give vitamin K antagonists time to reach therapeutic levels. 166 Later recurrences are the norm and may be reduced by early treatment with heparin. 167 Among patients treated with acencoumarol alone, 12 of 60 (20%) suffered a recurrent DVT or PE within 6 months.

Abbreviations: CTA, computed tomographic pulmonary angiography; CTV, venous phase venogram. 14 TABLE 13. Negative predictive values of CTA and CTA/CTV in relation to prior clinical assessment High Prob Clin Intermediate Low Prob Clin (Wells Score >6) Prob Clin (Wells Score 2-6) (Wells Score <2) PE Neg/CT Neg (%) PE Neg/CT Neg (%) PE Neg/CT Neg (%) CTA NEG CTA and CTV NEG 9/15 (60) 9/11 (82) 121/136 (89) 114/124 (92) 158/164 (96) 146/151 (97) Only patients with a reference test diagnosis by V/Q scan or conventional pulmonary DSA were included.

E. Dalen: In patients with a history of VTE, or with risk factors for VTE, who embark on prolonged travel, repetitive ankle flexion may be helpful and graduated compression stockings should be considered. 352 Curr Probl Cardiol, July 2010 FIG 23. Time-averaged peak blood velocity in the right popliteal vein at rest while supine, during ankle exercise while supine, sitting at rest, and sitting in healthy subjects with ankle exercise. 0001). Values shown are mean and 95% confidence interval. 165) Heparin in the Treatment of Acute Pulmonary Embolism The rationale for initial treatment with UFH or LMWH is to rapidly prevent the formation of new thrombi in the lower extremities while giving thrombi already present time to adhere to the venous walls, and to give vitamin K antagonists time to reach therapeutic levels.

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Acute Pulmonary Embolism - Current Problems in Cardiology-Vol.35, July 2010 No. 7, p307 by Paul D. Stein, MD, and Fadi Matta, MD


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